Therapeutic Drug Monitoring


The quantification of drugs in a matrix (whole blood or plasma) permit to guarantee an adapted dosage for the patient within the therapeutic window, in order to optimize their clinical benefits. The aim of this quantification is to ensure drug efficacy and to reduce the pharmacokinetic effects (sides effects). The exact measurement of these substances is therefore essential.

The mass spectrometry method is the best way to quantify these molecules in such complex matrices. Based on its strong expertise to produce labeled internal standard with stable isotopes, Alsachim, a Shimadzu Group company, developed reagent diagnostic kits enabling the simultaneous quantification of different drugs for Therapeutic Drug Monitoring (TDM).