Shim-pack GISS Series

Shim-pack GISS Series

 

High-speed analysis with ultra-high inertness and high durability

 

Shim-pack GISS series maintains the same ultra-high inertness and wider pH range as the Shim-pack GIST series while providing rapid separations with symmetric peaks. The optimization of surface area, pore size and chemical bonding delivers superior peak shapes, making these columns ideal for LC/MS/MS analysis.
Shim-pack GISS series also includes the 1.9μm and 3μm HP series for UHPLC analyses.

Analysis Examples

 


β-blocker

  Conditions
   Q1 > Q3
 1. Acebutolol  337.10 > 116.05 (+)
 2. Atenolol  267.25 > 145.00 (+)
 3. Labetalol  329.00 > 161.95 (+)
 4. Nadolol  310.05 > 254.00 (+)
 5. Pindolol  249.80 > 116.00 (+)

 

Conditions

 Column  Shim-pack GISS C18 (50 mmL x 2.1 mmI.D., 1.9 μm)
 Eluent  A) 10 mM Ammonium Formate in H2O
 B) 10 mM Ammonium Formate in CH3OH
 A/B = 70/30 ‒ 0.3min - 40/60 ‒ 0.5min - 0/100 ‒ 0.1min ‒ 0/100 ‒ 0.01min -70/30 ‒ 0.5min - 70/30, v/v
 Flow Rate  0.6 mL/min
 Col. Temp.  40 °C
 Detection  LC/MS/MS(ESI, Positive, Negative MRM)

 

Specifications

 

  Shim-pack GISS C18
Bonded Phase Octadecyl Groups
Analysis Mode Reversed Phase
Features High-speed analysis with ultra-high inertness and high durability
Particle Size (μm) 1.9, 3, 5
Pore Size (nm) 20
Surface Area (m2/g) 200
Carbon Loading (%) 9
End Cap
Inertness ▶▶▶▶▶
pH Range 1-10