LC-MS reagent kit for anticoagulants in plasma

DOSINACO™ for anticoagulants in plasma

Alsachim, a Shimadzu Group Comapny, developed DOSINACO™, a reagent kit enabling the simultaneous quantification of 9 anticoagulants in plasma (Acenocoumarol, Apixaban, Argatroban, Betrixaban, Dabigatran, Edoxaban, Fluindione, Rivaroxaban and Warfarin) using LC-MS/MS.
DOSINACO™ is the first Multiplex reagent kit for anticoagulants in the market.
The kit is a ready-to-use diagnostic device with all the components and accessories required to monitor anticoagulants in patient sample.

DOSINACO™ a turnkey solution:


Ready-to-use LC-MS reagent kit for immunosuppressants in plasma

  • 3 sets composed by: calibrator Set (with 6 levels and blank), Internal Standard Set and Control Set (with 4 levels)
  • Ready-to-use consumables: Mobile Phase A, Mobile Phase B, System Cleaning Phase, extraction and reconstitution buffer, analytical & trap columns, LC vials, microtubes


DOSINACO™ is available for 200 analysis and delivered with all documentation (analytical and sample method, quality data sheet, etc.).
The kit of 200 analyses is composed of: Mobiles Phases A & B, Cleaning phase, extraction/reconstitution buffer, Controls, Calibrators, Internal Standards and analytical column.

The kit can be customized tailored to your specific requirements (number of analysis). Please contact us to explain your specific needs or to arrange a demo:

DOSINACO™ benefits:

  • First Multiplex kit for anticoagulants
  • Ready-to-use
  • Supported by the manufacturer
  • Consistent QC material available

Order information:

RUO Version Full kit
227-40500-58 DOSINACO™ Kit for 200 Analysis


RUO Version Individual Kit-Components / Content per Kit: Qty in Kit of 200
227-40502-58 DOSINACO™, Mobile Phase A (1 L) 1
227-40503-58 DOSINACO™, Mobile Phase B (1 L) 1
227-40504-58 DOSINACO™, System Cleaning Phase (1 L) 1
227-40505-58 DOSINACO™, Extraction Buffer (100 mL) 1
227-40506-58 DOSINACO™, Internal Standard Set (3 x 2,5 mL + 15 mL Recon. Buffer) 1
227-40510-58 DOSINACO™, Calibrator Set (6 Levels + Blank (500 μL each)) 2
227-40520-58 DOSINACO™, Control Set (4 Levels (500 μL each)) 2
227-40531-58 DOSINACO™, Analytical Column 1


RUO Version Optional parts
227-40335-58 DOSINACO™, Microtubes (500 pcs)
227-40343-58 DOSINACO™, LC Vial Set (100 LC Vials and Caps)
227-40540-58 DOSINACO™, Tuning Mix, labeled
227-40541-58 DOSINACO™, Tuning Mix, unlabeled

DOSINACO™ is a registered trademark of Alsachim, a Shimadzu Group Company. This page may contain references to products that are not available in your country. This product could be available for research use only depending of your country. Please contact us to check the availability of these products in your country:

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