UFsensitivityTM

■ Heated ESI Probe



In order to improve desolvation efficiency, the newly developed heated ESI probe combines a high-temperature gas with the nebulizer spray, assisting in the desolvation of large droplets and facilitating ionization. This development allows for high-sensitivity analysis of a wide range of target compounds.

■ Excellent Reproducibility Even at Attogram (ag) Levels

Both sensitivity and reproducibility are essential when establishing low limits of quantitation. High-precision quantitative results obtained with the LCMS-8050 in the analysis of Verapamil in blood plasma at levels between 500 ag and 50 pg are shown below. Excellent reproducibility with a % RSD of 2.77 % was obtained when analyzing just 500 ag of Verapamil. The LCMS-8050 demonstrates optimal performance for quantitative analysis of even trace components of a complex matrix.

Concentration actual ng/mL	Calculated concentration ng/mL	% RSD (n = 6)	Accuracy (%) (n = 6)
0.000500	0.000501	2.77	100.2
0.00500	0.00496	3.98	99.2
0.0500	0.0506	1.21	101.2
0.500	0.493	1.31	98.6
5.00	4.89	1.81	97.8
50.0	51.6	0.65	103.2