UFsensitivity™
UFsensitivityTM
High Sensitivity for Trace Quantitative Analysis
■ Heated ESI Probe
In order to improve desolvation efficiency, the newly developed heated ESI probe combines a high-temperature gas with the nebulizer spray, assisting in the desolvation of large droplets and facilitating ionization. This development allows for high-sensitivity analysis of a wide range of target compounds.
■ Excellent Reproducibility Even at Attogram (ag) Levels
Both sensitivity and reproducibility are essential when establishing low limits of quantitation. High-precision quantitative results obtained with the LCMS-8050 in the analysis of Verapamil in blood plasma at levels between 500 ag and 50 pg are shown below. Excellent reproducibility with a % RSD of 2.77 % was obtained when analyzing just 500 ag of Verapamil. The LCMS-8050 demonstrates optimal performance for quantitative analysis of even trace components of a complex matrix.
| Concentration actual ng/mL |
Calculated concentration ng/mL |
% RSD (n = 6) |
Accuracy (%) (n = 6) |
|---|---|---|---|
| 0.000500 | 0.000501 | 2.77 | 100.2 |
| 0.00500 | 0.00496 | 3.98 | 99.2 |
| 0.0500 | 0.0506 | 1.21 | 101.2 |
| 0.500 | 0.493 | 1.31 | 98.6 |
| 5.00 | 4.89 | 1.81 | 97.8 |
| 50.0 | 51.6 | 0.65 | 103.2 |
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